Spire’s biomedical R&D initiatives are in the areas of biomaterials and biophotonics life sciences.

Biomaterials

Spire R&D develops custom coatings and surface treatments that have applications for products including orthopedic, cardiovascular and neurological devices and instruments. These coatings and surface treatments enhance performance of these devices and instruments by adding or improving one or more of the following properties:

Lubricity Friction Hardness Wear resistance Infection resistance Hydrophilicity Hydrophobicity

Corrosion resistance Permeation resistance Biocompatibility Radiopacity Hemocompatibility Adhesion Electrical insulation and conductivity

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Biophotonics Life Sciences

Leveraging its extensive government funded research activities, Spire R&D has established a major biophotonics life science initiative aimed at developing new types of laser-based components and semiconductor-related services for the life sciences instruments market. As a key technology for genomics and optical instruments that characterize DNA and biological agents, biophotonics offers exciting growth opportunities for Spire.

Spire R&D has been awarded a number of US federal contracts in these areas, including a Center for Disease Control (CDC) grant for designing a portable optical instrument for plague detection and a National Institutes of Health (NIH) grant to develop a new fiber laser-based instrument for glaucoma surgery.

Examples of biophotonics instruments that have been, or are currently being developed at Spire R&D include:

Neural recording microelectrodes Cerebral oxygen monitor Optical plague detector Non-invasive glucose monitor using terahertz radiation Portable x-ray imagers

Silicon-based sensors for bioagent detection Field deployable assay for bacteria detection Fiber laser instrument for eye surgery

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